Description

2-[2-[2-(4-Nitrophenoxy)Ethoxy]Ethoxy]Ethanol is a specialized organic compound featuring a polyethylene glycol (PEG) linker terminated with a nitrophenyl ether group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular assembly and functionalization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for attaching functional groups via its reactive termini.
• Linker for Bioconjugation: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates, leveraging the PEG spacer to improve solubility and pharmacokinetics.
• Polymer Chemistry: Serves as a monomer or chain extender in the creation of functionalized polymers and dendrimers with specific light-responsive or cleavable properties.
• Material Science: Employed in the surface modification of nanoparticles and the fabrication of smart materials where the nitro group can be further reduced or transformed.
• Research & Development: A versatile tool in organic synthesis for constructing complex ether-linked architectures in academic and industrial R&D settings.
• Agrochemical Synthesis: Used as an intermediate in the production of advanced crop protection agents requiring specific solubility and delivery characteristics.

Basic Information

Product Name	2-[2-[2-(4-Nitrophenoxy)Ethoxy]Ethoxy]Ethanol
CAS No.	63134-26-9
Molecular Formula	C₁₂H₁₇NO₆
Molecular Weight	271.27 g/mol
Synonyms	4-Nitrophenyl-triethylene glycol ether; 2,2'-[2-(4-Nitrophenoxy)ethoxy]diethanol; 4-Nitrophenol ethoxylate (3 EO); Triethylene glycol mono(4-nitrophenyl) ether; PEG3 4-nitrophenyl ether; 4-Nitrophenyl-PEG3-OH; 2-[2-(2-(4-Nitrophenoxy)ethoxy)ethoxy]ethanol; 4-NP-PEG3-alcohol
EINECS	Contact for details

Quality Control

Our production of 2-[2-[2-(4-Nitrophenoxy)Ethoxy]Ethoxy]Ethanol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.