Description

8-Fluoro-4-Hydroxyquinoline is a fluorinated quinoline derivative that serves as a versatile and high-value pharmaceutical intermediate. Its core value lies in the strategic incorporation of fluorine, which can significantly enhance the biological activity, metabolic stability, and bioavailability of target drug molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in antimicrobial, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can improve efficacy and environmental profile.
• Material Science Research: Acts as a precursor for the development of organic electronic materials, ligands for catalysis, and fluorescent probes.
• Chemical Biology: Employed as a molecular scaffold or tag in probe development for studying biological systems and enzyme mechanisms.
• Academic & Contract Research: Serves as a critical reagent for synthetic organic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	8-Fluoro-4-Hydroxyquinoline
CAS No.	63010-71-9
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	8-Fluoro-4-quinolinol; 4-Hydroxy-8-fluoroquinoline; 8-Fluoro-4-hydroxyquinoline; 8-Fluoroquinolin-4-ol; 4-Quinolinol, 8-fluoro-; 8-Fluoro-4-quinolone
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4-Hydroxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.