Description

8-Chloro-4-Hydroxy-5-Methoxyquinoline-3-Carboxylic Acid is a high-purity, synthetically versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and functionalized structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating compounds with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in developing advanced fungicides, herbicides, and plant growth regulators due to its bioactive quinoline core.
• Material Science: Serves as a functional monomer or ligand for creating specialized polymers, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Synthesis: Employed as a versatile scaffold for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.
• Dye & Pigment Industry: Acts as an intermediate in the production of specialized quinoline-based dyes and fluorescent markers.
• Analytical Reference Standard: Supplied as a certified reference material (CRM) for quality control and analytical method development in regulatory and research laboratories.

Basic Information

Product Name	8-Chloro-4-Hydroxy-5-Methoxyquinoline-3-Carboxylic Acid
CAS No.	63010-42-4
Molecular Formula	C11H8ClNO4
Molecular Weight	253.64 g/mol
Synonyms	8-Chloro-4-hydroxy-5-methoxyquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 8-chloro-4-hydroxy-5-methoxy-; 8-Chloro-5-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 5-Methoxy-8-chloro-4-hydroxyquinoline-3-carboxylic acid; 8-Chloro-4-hydroxy-5-methoxy-3-quinolinecarboxylic acid; 63010-42-4; CAS 63010-42-4
EINECS	Contact for details

Quality Control

Our 8-Chloro-4-Hydroxy-5-Methoxyquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.