Description

5-Acetyl-8-Hydroxy-1H-Quinolin-2-One is a specialized quinoline derivative that serves as a crucial synthetic intermediate and building block in advanced organic chemistry. Its unique acetyl and hydroxy substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers involved in synthesizing active pharmaceutical ingredients (APIs), fine chemicals, and functional materials, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antimicrobial and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and complex organic compounds requiring specific quinoline frameworks.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	5-Acetyl-8-Hydroxy-1H-Quinolin-2-One
CAS No.	62978-73-8
Molecular Formula	C11H9NO3
Molecular Weight	203.19 g/mol
Synonyms	8-Hydroxy-5-acetyl-1H-quinolin-2-one; 5-Acetyl-8-hydroxyquinolin-2(1H)-one; 2(1H)-Quinolinone, 5-acetyl-8-hydroxy-; 5-Acetyl-8-hydroxy-2(1H)-quinolinone; 8-Hydroxy-5-acetyl-2-quinolinone
EINECS	Contact for details

Quality Control

Our 5-Acetyl-8-Hydroxy-1H-Quinolin-2-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.