Description

(3R)-2,3,4,10-Tetrahydro-3-Hydroxy-2,2,10-Trimethyl-5H-Pyrano[2,3-B]Quinolin-5-One is a high-purity, optically active quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex molecules with specific biological activities. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Advanced Organic Synthesis: Utilized as a sophisticated building block for constructing complex natural product analogs and heterocyclic compounds.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the study and development of new asymmetric catalytic reactions.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical laboratories.
• Material Science Research: Investigated as a precursor for novel organic electronic materials or specialty dyes due to its fused quinoline-pyran structure.

Basic Information

Product Name	(3R)-2,3,4,10-Tetrahydro-3-Hydroxy-2,2,10-Trimethyl-5H-Pyrano[2,3-B]Quinolin-5-One
CAS No.	62928-56-7
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.35 g/mol
Synonyms	(3R)-3-Hydroxy-2,2,10-trimethyl-2,3,4,10-tetrahydro-5H-pyrano[2,3-b]quinolin-5-one; (R)-Flindersine derivative; (3R)-3-Hydroxy-2,2,10-trimethyl-2,3,4,10-tetrahydro-5H-pyrano[2,3-b]quinolin-5-one; 5H-Pyrano[2,3-b]quinolin-5-one, 2,3,4,10-tetrahydro-3-hydroxy-2,2,10-trimethyl-, (3R)-; (R)-2,2,10-Trimethyl-3-hydroxy-2,3,4,10-tetrahydro-5H-pyrano[2,3-b]quinolin-5-one
EINECS	Contact for details

Quality Control

Our (3R)-2,3,4,10-Tetrahydro-3-Hydroxy-2,2,10-Trimethyl-5H-Pyrano[2,3-B]Quinolin-5-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.