Description

Carbodine CAS NO 62805-43-0 is a specialized chemical compound, also known as 1,1'-Carbonyldiimidazole (CDI), widely recognized as a versatile coupling and activating agent in organic synthesis. Its primary value lies in its ability to facilitate the formation of amides, esters, and peptides under mild conditions, offering a safer and cleaner alternative to traditional reagents like acid chlorides. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and biotechnology sectors, where precise and efficient synthesis is critical.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the preparation of active pharmaceutical ingredients (APIs), particularly in amide and peptide bond formation.
• Peptide Chemistry: Used as a coupling agent in solid-phase and solution-phase peptide synthesis to minimize racemization.
• Agrochemical Production: Employed in the synthesis of herbicides, fungicides, and other crop protection agents requiring high chemical selectivity.
• Polymer Chemistry: Acts as a monomer or chain extender in the production of polyurethanes, polycarbonates, and other specialty polymers.
• Bioconjugation: Facilitates the labeling and cross-linking of biomolecules for diagnostic and research applications.
• Chemical Derivatization: Used to activate carboxylic acids for subsequent reactions in analytical chemistry and material science.

Basic Information

Product Name	Carbodine
CAS No.	62805-43-0
Molecular Formula	C7H6N4O
Molecular Weight	162.15 g/mol
Synonyms	1,1'-Carbonyldiimidazole (CDI); N,N'-Carbonyldiimidazole; CDI; Imidazole, 1,1'-carbonylbis-; Carbonyldiimidazole; 1,1'-Carbonylbisimidazole; NSC 93619
EINECS	263-473-6

Quality Control

Our Carbodine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, IR for identification, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can compromise product integrity. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	115 - 120 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.