Description

Ribose-5-Triphosphate (R5P) is a critical phosphorylated ribose sugar and a key intermediate in the pentose phosphate pathway and nucleotide biosynthesis. Its significance lies in its role as a direct precursor for the synthesis of nucleotides, coenzymes, and various bioactive molecules essential for cellular metabolism. This high-purity biochemical is primarily required by manufacturers in the pharmaceutical, biotechnology, and life science research sectors for applications in enzymatic synthesis, metabolic studies, and as a raw material for high-value nucleotide derivatives.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of nucleoside analogs, antiviral drugs, and other nucleotide-based active pharmaceutical ingredients (APIs).
• Biochemical Research & Diagnostics: Used as a substrate or standard in enzymatic assays, metabolic pathway studies, and diagnostic kit development.
• Enzyme Cofactor Synthesis: Acts as a precursor in the production of essential coenzymes like NAD(P)H and Coenzyme A.
• Cell Culture & Media Supplement: Employed in specialized cell culture media to support nucleotide synthesis in fast-growing or engineered cell lines.
• Cosmetic & Nutraceutical Ingredient: Investigated for use in high-end skincare formulations and dietary supplements targeting cellular energy and repair.

Basic Information

Product Name	Ribose-5-Triphosphate
CAS No.	62746-84-3
Molecular Formula	C5H15O14P3
Molecular Weight	428.09 g/mol
Synonyms	Ribose 5-triphosphate; D-Ribose-5-triphosphate; 5-O-[(Phosphonooxy)phosphinyl] D-ribofuranose; R5P; P-Rib-PP; Pentose phosphate pathway intermediate; D-Ribofuranose, 5-(trihydrogen diphosphate), 1-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our Ribose-5-Triphosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and production. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, temperature-controlled environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 5.0%
pH (1% Solution)	5.0 - 7.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.