Description

4'-[(2S)-2-Methylbutyl]-[1,1'-Biphenyl]-4-Carboxylic Acid is a chiral biphenyl derivative carboxylic acid, serving as a critical advanced pharmaceutical intermediate and a versatile building block in asymmetric synthesis. Its value lies in its defined stereochemistry and functional groups, enabling the construction of complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug discovery.
• Asymmetric Synthesis: Utilized as a starting material or ligand precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Agrochemical Research: Intermediate in the development of new-generation herbicides and pesticides with improved efficacy and selectivity.
• Liquid Crystal Materials: Potential precursor for chiral dopants or components in advanced liquid crystal displays (LCDs) and optical materials.
• Organic Electronic Materials: Building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and photovoltaics.
• Chemical Research & Development: Serves as a valuable tool compound for method development and exploring new reaction pathways in academic and industrial R&D labs.

Basic Information

Product Name	4'-[(2S)-2-Methylbutyl]-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	62614-48-6
Molecular Formula	C18H20O2
Molecular Weight	268.35 g/mol
Synonyms	(2S)-2-Methylbutyl-4-biphenylcarboxylic Acid; (S)-4'-(2-Methylbutyl)biphenyl-4-carboxylic Acid; [1,1'-Biphenyl]-4-carboxylic Acid, 4'-[(2S)-2-methylbutyl]-; (S)-2-Methylbutyl-4-biphenylcarboxylic Acid; Biphenyl-4-carboxylic Acid, 4'-[(2S)-2-methylbutyl]-; (S)-4'-(2-Methylbutyl)-[1,1'-biphenyl]-4-carboxylic Acid; CAS 62614-48-6
EINECS	Contact for details

Quality Control

Our production of 4'-[(2S)-2-Methylbutyl]-[1,1'-Biphenyl]-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and IR for structural confirmation, and precise titration for assay determination. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.