Description

3-Bromo-4'-Methanesulfonyl-Biphenyl is a high-purity biphenyl derivative functionalized with bromine and a methanesulfonyl group, serving as a versatile and critical building block in advanced organic synthesis. Its molecular architecture makes it particularly valuable for constructing complex molecules where precise electronic and steric properties are required. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, especially in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in kinase inhibitor and receptor antagonist programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its biphenyl core for biological activity.
• Material Science Research: Acts as a precursor for organic electronic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form more complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Fine Chemical Production: Serves as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	3-Bromo-4'-Methanesulfonyl-Biphenyl
CAS No.	62579-54-8
Molecular Formula	C₁₃H₁₁BrO₂S
Molecular Weight	311.20 g/mol
Synonyms	[1,1'-Biphenyl]-3-bromo-4'-methanesulfonyl; 3-Bromo-4'-(methylsulfonyl)biphenyl; 4'-Methanesulfonyl-3-bromobiphenyl; 3-Bromo-4'-methylsulfonylbiphenyl; 3-Bromobiphenyl-4'-yl methyl sulfone; (3-Bromo-[1,1'-biphenyl]-4-yl)(methyl)sulfone
EINECS	Contact for details

Quality Control

Our 3-Bromo-4'-Methanesulfonyl-Biphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.