Description

2-Chloro-8-Methyl-4(3H)-Quinazolinone is a versatile and high-value heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique quinazolinone core, functionalized with chloro and methyl groups, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex quinazolinone-based libraries for high-throughput screening.
• Material Science: Investigated as a monomer or additive for creating specialty polymers and organic electronic materials due to its fused aromatic system.
• Biochemical Tool Compound: Serves as a scaffold for developing fluorescent probes or enzyme inhibitors used in biochemical assays and diagnostic research.

Basic Information

Product Name	2-Chloro-8-Methyl-4(3H)-Quinazolinone
CAS No.	62484-40-6
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	2-Chloro-8-methyl-3,4-dihydroquinazolin-4-one; 8-Methyl-2-chloro-4(3H)-quinazolinone; 2-Chloro-8-methylquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 2-chloro-8-methyl-; 2-Chloro-8-methyl-4-quinazolinol; 2-Chloro-8-methyl-4-hydroxyquinazoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Methyl-4(3H)-Quinazolinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.