Description

trans-Methyl-4-Aminocyclohexanecarboxylate is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its rigid cyclohexane backbone and strategically positioned amino and ester functional groups make it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its structural properties to enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The trans-4-aminocyclohexanecarboxylic acid scaffold is valuable for creating conformationally restricted peptide analogs.
• Fine Chemical Production: Intermediate for specialty chemicals, dyes, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	trans-Methyl-4-Aminocyclohexanecarboxylate
CAS No.	62456-15-9
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-Methyl 4-aminocyclohexanecarboxylate; Methyl trans-4-aminocyclohexanecarboxylate; trans-4-(Methoxycarbonyl)cyclohexylamine; (1r,4r)-4-(Methoxycarbonyl)cyclohexanamine; Methyl (trans-4-aminocyclohexane)carboxylate; 4-Aminocyclohexanecarboxylic acid methyl ester, trans-; Methyl 4-aminocyclohexanecarboxylate (trans isomer)
EINECS	Contact for details

Quality Control

Our trans-Methyl-4-Aminocyclohexanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% trans isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.