Description

Bis[(9R)-9-Hydroxy-6'-Methoxycinchonanium] Sulphate is a high-purity, non-racemic cinchona alkaloid derivative salt, valued for its role as a versatile chiral catalyst and resolving agent in asymmetric synthesis. Its primary commercial significance lies in enabling the production of enantiomerically pure pharmaceutical intermediates and fine chemicals, which are critical for modern drug development. This compound is essential for research institutions, pharmaceutical manufacturers, and specialty chemical companies focused on stereoselective synthesis and chiral separations.

Application

• As a chiral phase-transfer catalyst (PTC) for asymmetric alkylation and other carbon-carbon bond-forming reactions.
• As a resolving agent for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• In the synthesis of enantiomerically enriched intermediates for active pharmaceutical ingredients (APIs).
• As a key component in chiral stationary phases for analytical and preparative chromatography.
• For fundamental research and development in organic chemistry and catalysis.
• In the production of specialty fine chemicals where high stereochemical purity is required.

Basic Information

Product Name	Bis[(9R)-9-Hydroxy-6'-Methoxycinchonanium] Sulphate
CAS No.	62409-09-0
Molecular Formula	C₄₂H₅₂N₄O₈S
Molecular Weight	772.95 g/mol
Synonyms	(9R)-9-Hydroxy-6'-methoxycinchonan-9-ium sulfate (2:1); Bis[(9R)-9-hydroxy-6'-methoxycinchonan-9-ium] sulfate; Cinchonidine derivative sulfate salt; (R)-9-Hydroxy-6'-methoxycinchonan-9-ium sulfate (1:2); Chiral cinchona alkaloid ammonium salt; Asymmetric phase-transfer catalyst PTC derivative.
EINECS	Contact for details

Quality Control

Our Bis[(9R)-9-Hydroxy-6'-Methoxycinchonanium] Sulphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical assay, and impurity profile. We support compliance with cGMP guidelines for pharmaceutical applications, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.