Description

D-Threonine Ethyl Ester Hydrochloride is a high-purity, non-natural amino acid derivative used as a critical chiral building block in organic synthesis. This compound is essential for the research and development of novel pharmaceuticals, particularly in the creation of peptidomimetics and active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected D-threonine derivative in solid-phase and solution-phase peptide chemistry.
• Asymmetric Catalysis Research: Serves as a chiral auxiliary or ligand precursor in the development of new catalytic systems.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the design of novel bioactive compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to probe stereospecificity.
• Fine Chemical Production: A building block for the manufacture of specialty chemicals, agrochemicals, and advanced materials.

Basic Information

Product Name	D-Threonine Ethyl Ester Hydrochloride
CAS No.	62365-20-2
Molecular Formula	C6H14ClNO3
Molecular Weight	183.63 g/mol
Synonyms	D-Threonine ethyl ester HCl; (2R,3S)-2-Amino-3-hydroxybutanoic acid ethyl ester hydrochloride; Ethyl (2R,3S)-2-amino-3-hydroxybutanoate hydrochloride; D-Threonine O-ethyl ester hydrochloride; (R*,S*)-2-Amino-3-hydroxybutyric acid ethyl ester hydrochloride; D-allo-Threonine ethyl ester hydrochloride; Ethyl D-threoninate hydrochloride
EINECS	Contact for details

Quality Control

Our D-Threonine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.