Description

(1S)-1β-Bromo-4,10Aβ-Dimethyl-8β-Isopropyl-8Aα-(Bromomethyl)-1,2,3,4,4Aα,4Bβ,7,8,8A,9,10,10A-Dodecahydrophenanthrene-4β-Ol is a high-purity, complex brominated diterpenoid derivative that serves as a critical chiral building block and synthetic intermediate. Its unique sterically hindered polycyclic structure makes it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel therapeutic agents, natural product synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for complex natural product analogs and steroidal frameworks.
• Organic Synthesis Research: Advanced building block for methodological studies in stereoselective synthesis, C-H functionalization, and cross-coupling reactions.
• Natural Product Chemistry: Used in the semi-synthesis or total synthesis of complex diterpenoids and related natural products for biological evaluation.
• Material Science Research: Potential monomer or precursor for developing specialized polymers or liquid crystals with unique structural properties.
• Chemical Biology: Serves as a probe or scaffold for developing enzyme inhibitors or receptor ligands due to its rigid, three-dimensional structure.
• Catalyst Development: Can be utilized as a ligand precursor for designing novel chiral catalysts in asymmetric synthesis.

Basic Information

Product Name	(1S)-1β-Bromo-4,10Aβ-Dimethyl-8β-Isopropyl-8Aα-(Bromomethyl)-1,2,3,4,4Aα,4Bβ,7,8,8A,9,10,10A-Dodecahydrophenanthrene-4β-Ol
CAS No.	62326-56-1
Molecular Formula	C21H34Br2O
Molecular Weight	462.31 g/mol
Synonyms	(1S)-1β-Bromo-4,10aβ-dimethyl-8β-isopropyl-8aα-(bromomethyl)-1,2,3,4,4aα,4bβ,7,8,8a,9,10,10a-dodecahydrophenanthren-4β-ol; 1β-Bromo-4,10aβ-dimethyl-8β-isopropyl-8aα-(bromomethyl)-1,2,3,4,4aα,4bβ,7,8,8a,9,10,10a-dodecahydrophenanthren-4β-ol; Brominated Dodecahydrophenanthrene Derivative; Diterpenoid Bromohydrin Intermediate; CAS 62326-56-1
EINECS	Contact for details

Quality Control

Our (1S)-1β-Bromo-4,10Aβ-Dimethyl-8β-Isopropyl-8Aα-(Bromomethyl)-1,2,3,4,4Aα,4Bβ,7,8,8A,9,10,10A-Dodecahydrophenanthrene-4β-Ol is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and MS to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.