Description

6-Chloro-2-Chloromethyl-4-Phenylquinazoline 3-Oxide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring quinazoline-based scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new drug candidates and specialized chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex quinazoline N-oxide derivatives and studying their chemical properties.
• Agrochemical Development: Serves as a precursor in the research and development of new herbicides and pesticides with specific modes of action.
• Material Science: Investigated for the creation of specialized organic ligands and functional materials.

Basic Information

Product Name	6-Chloro-2-Chloromethyl-4-Phenylquinazoline 3-Oxide Hydrochloride
CAS No.	62299-17-6
Molecular Formula	C16H11Cl2N2O·HCl
Molecular Weight	365.64 g/mol
Synonyms	6-Chloro-2-(chloromethyl)-4-phenylquinazoline 3-oxide hydrochloride; 2-Chloromethyl-6-chloro-4-phenylquinazoline 3-oxide hydrochloride; Quinazoline, 6-chloro-2-(chloromethyl)-4-phenyl-, 3-oxide, hydrochloride; 4-Phenyl-6-chloro-2-chloromethylquinazoline 3-oxide hydrochloride; 62299-17-6; CCRIS 9381
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Chloromethyl-4-Phenylquinazoline 3-Oxide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.