Description

2-Ethyl-5,6,7,8-Tetrahydrospiro[4H-1,3,2-Benzodioxaborin-4,1'-Cyclohexane] is a sophisticated spirocyclic organoboron compound, valued for its unique structural motif and reactivity as a key synthetic intermediate. Its significance lies in enabling complex molecular construction, particularly in the synthesis of novel pharmaceutical scaffolds and advanced materials. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to leverage boron chemistry for innovative applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting complex disease pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the spirocyclic boron moiety can impart unique biological activity.
• Material Science: Acts as a precursor or monomer in the creation of advanced polymers, ligands for catalysis, and boron-doped organic electronic materials.
• Cross-Coupling Reactions: Functions as an organoboron reagent (boronic ester equivalent) in Suzuki-Miyaura and other metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical space in medicinal and synthetic chemistry laboratories.

Basic Information

Product Name	2-Ethyl-5,6,7,8-Tetrahydrospiro[4H-1,3,2-Benzodioxaborin-4,1'-Cyclohexane]
CAS No.	62238-27-1
Molecular Formula	C14H23BO2
Molecular Weight	234.14 g/mol
Synonyms	2-Ethyl-5,6,7,8-tetrahydrospiro[1,3,2-benzodioxaborinine-4,1'-cyclohexane]; 2-Ethyl-5,6,7,8-tetrahydrospiro[4H-1,3,2-benzodioxaborin-4,1'-cyclohexane]; Spiro[1,3,2-benzodioxaborinine-4,1'-cyclohexane], 2-ethyl-5,6,7,8-tetrahydro-; 2-Ethyl-5,6,7,8-tetrahydrospiro[benzo[d][1,3,2]dioxaborinine-4,1'-cyclohexane]; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 2-Ethyl-5,6,7,8-Tetrahydrospiro[4H-1,3,2-Benzodioxaborin-4,1'-Cyclohexane] is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization including NMR, HPLC, and GC to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.