Description

4-Fluoro-4-Deoxy-D-Glucose is a fluorinated glucose analog, a key intermediate in the synthesis of advanced radiopharmaceuticals and biochemical probes. Its primary value lies in its role as a precursor for positron emission tomography (PET) tracers, enabling critical research and diagnostic applications in oncology and neurology. This high-purity compound is essential for pharmaceutical R&D laboratories, diagnostic imaging centers, and academic institutions focused on metabolic studies and radiochemistry.

Application

• Radiopharmaceutical Synthesis: A crucial precursor for the production of [18F]FDG (Fludeoxyglucose F 18), the most widely used PET tracer in clinical oncology and neurology.
• Biochemical Research: Used as a stable, non-radioactive analog to study glucose transport mechanisms and hexokinase enzyme activity in cell cultures and tissue samples.
• Diagnostic Agent Development: Serves as a key intermediate in the research and development of novel fluorine-18 labeled diagnostic imaging agents.
• Metabolic Pathway Studies: Employed in academic and industrial research to investigate glycolysis inhibition and tumor metabolism.
• Reference Standard: Used as a high-purity chemical reference standard (CRS) for quality control in PET tracer manufacturing and analytical method validation.

Basic Information

Product Name	4-Fluoro-4-Deoxy-D-Glucose
CAS No.	62182-11-0
Molecular Formula	C6H11FO5
Molecular Weight	182.15 g/mol
Synonyms	4-Fluoro-4-deoxy-D-glucose; 4-FDG; 4-Fluoro-D-glucose; 4-Fluoroglucose; 4-Deoxy-4-fluoro-D-glucose; D-4-Fluoroglucose; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-fluorooxane-2,3,4-triol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-4-Deoxy-D-Glucose is manufactured under strict quality management systems to ensure the high purity and consistency required for sensitive radiopharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.