Description

Z-Glu(Obzl)-Oh Dcha is a protected glutamic acid derivative, specifically the benzyl ester of N-carbobenzyloxy-L-glutamic acid as a dicyclohexylamine (DCHA) salt. This compound is a crucial chiral building block and intermediate in the synthesis of complex peptides, pharmaceuticals, and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in advanced organic synthesis and peptide chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the production of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected glutamic acid residue in solid-phase and solution-phase peptide synthesis, preventing unwanted side reactions.
• Biochemical Research: Used as a standard or reagent in studies involving glutamate receptors, neurotransmitters, and metabolic pathways.
• Fine Chemical Production: Intermediate for manufacturing specialized chemicals, catalysts, and ligands used in asymmetric synthesis.
• Protecting Group Chemistry: The carbobenzyloxy (Cbz) and benzyl ester groups allow for selective deprotection strategies in multi-step syntheses.

Basic Information

Product Name	Z-Glu(Obzl)-Oh Dcha
CAS No.	62121-03-3
Molecular Formula	C26H33NO6 • C12H23N
Molecular Weight	583.71 g/mol (free acid: 385.43 g/mol)
Synonyms	N-Carbobenzyloxy-L-glutamic acid α-benzyl ester dicyclohexylamine salt; Z-L-Glu(OBzl)-OH • DCHA; Nα-Cbz-L-glutamic acid 1-benzyl ester dicyclohexylammonium salt; (S)-2-(((Benzyloxy)carbonyl)amino)pentanedioic acid 1-benzyl ester compound with dicyclohexylamine; Cbz-Glu(OBzl)-OH DCHA salt; Z-Glu(OBzl)-OH DCHA; Z-Glutamic acid α-benzyl ester DCHA salt; N-Cbz-L-glutamic acid γ-benzyl ester dicyclohexylamine salt
EINECS	Contact for details

Quality Control

Our Z-Glu(Obzl)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.