Description

L-Alanine Isopropyl Ester Hydrochloride is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of pharmaceuticals and bioactive peptides. Its primary value lies in enabling the controlled introduction of the alanine moiety while protecting the carboxylic acid functionality, which is critical for complex multi-step syntheses. Target industries include pharmaceutical R&D, contract manufacturing organizations (CMOs), and fine chemical producers focused on peptide-based therapeutics and agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in peptide and peptidomimetic drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate L-alanine residues with a protected carboxyl group.
• Agrochemical Research: Serves as a building block for developing novel chiral herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Probe Development: Facilitates the chemical modification of biomolecules for diagnostic and research applications.
• Asymmetric Synthesis Catalyst Ligand: Can be utilized in the preparation of chiral ligands or catalysts for enantioselective transformations.
• Academic & Industrial R&D: A standard reagent in medicinal chemistry and organic synthesis laboratories for exploring new chemical entities.

Basic Information

Product Name	L-Alanine Isopropyl Ester Hydrochloride
CAS No.	62062-65-1
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	L-Alanine isopropyl ester HCl; (S)-2-Aminopropanoic acid 1-methylethyl ester hydrochloride; Isopropyl L-alaninate hydrochloride; Alanine isopropyl ester hydrochloride; L-Alanine-1-methylethyl ester hydrochloride; H-Ala-OiPr·HCl; (S)-1-Isopropoxy-1-oxopropan-2-aminium chloride
EINECS	Contact for details

Quality Control

Our L-Alanine Isopropyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research applications. Key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identity (by IR and NMR) are verified. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +20.0° (c=1 in H2O)
Chiral Purity (ee)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.