Description

4-Amino-L-Phenylalanine Hydrochloride is a high-purity, non-natural amino acid derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical chiral building block for the synthesis of complex peptides and bioactive molecules, offering researchers precise control over molecular structure. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a para-aminophenylalanine residue, enabling site-specific modifications.
• Bioconjugation & Labeling: The aromatic amine group provides a reactive handle for conjugation with fluorescent dyes, biotin, or other probes for creating diagnostic tools.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop enzyme inhibitors, receptor agonists/antagonists, and other bioactive compounds.
• Chemical Biology Probes: Integral for designing activity-based probes and photoaffinity labels to study protein function and interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical manufacturing and regulatory compliance.

Basic Information

Item	Detail
Product Name	4-Amino-L-Phenylalanine Hydrochloride
CAS No.	62040-55-5
Molecular Formula	C9H13ClN2O2
Molecular Weight	216.66 g/mol
Synonyms	L-4-Aminophenylalanine hydrochloride; (S)-2-Amino-3-(4-aminophenyl)propanoic acid hydrochloride; p-Amino-L-phenylalanine HCl; 4-Amino-L-Phe-OH·HCl; 4-Amino-DL-phenylalanine hydrochloride (mixture); Fmoc-4-Amino-L-Phenylalanine (precursor); PARA-AMINO-L-PHENYLALANINE HYDROCHLORIDE
EINECS	Contact for details

Quality Control

Our 4-Amino-L-Phenylalanine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.