Description

5-Bromo-2-Mercaptobenzoic Acid is a versatile sulfur-containing aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a thiol group ortho to a bromine substituent, makes it a critical precursor for constructing complex heterocycles and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly for molecules containing benzothiazole or related heterocyclic cores with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromine and thiol groups allow for further functionalization.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands in coordination chemistry and catalysis, especially for metal complexes involving sulfur donors.
• Material Science Research: Employed in the development of organic electronic materials, conductive polymers, and metal-organic frameworks (MOFs) due to its multifunctional aromatic backbone.
• Chemical Biology Probes: Useful for creating bioconjugation reagents or probes that target thiol-reactive sites in proteins and other biomolecules.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic laboratories engaged in custom organic synthesis and method development.

Basic Information

Product Name	5-Bromo-2-Mercaptobenzoic Acid
CAS No.	61954-80-1
Molecular Formula	C7H5BrO2S
Molecular Weight	233.08 g/mol
Synonyms	5-Bromo-2-sulfanylbenzoic acid; 2-Mercapto-5-bromobenzoic acid; 5-Bromosalicylic acid thiol; Benzoic acid, 5-bromo-2-mercapto-; 5-Bromo-2-thiosalicylic acid; 2-Sulfanyl-5-bromobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Mercaptobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage of bulk quantities. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.