Description

2,4-Dichloro-7,8-Dimethoxy-Quinazoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its dual reactive sites, which enable its use as a versatile precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Used in the design and synthesis of chemical probes and affinity tags for target identification and validation.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and advanced polymers with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2,4-Dichloro-7,8-Dimethoxy-Quinazoline
CAS No.	61948-62-7
Molecular Formula	C₁₁H₁₀Cl₂N₂O₂
Molecular Weight	273.12 g/mol
Synonyms	7,8-Dimethoxy-2,4-dichloroquinazoline; 2,4-Dichloro-7,8-dimethoxyquinazoline; Quinazoline, 2,4-dichloro-7,8-dimethoxy-; 2,4-Dichloro-7,8-bis(methoxy)quinazoline; 7,8-Dimethoxy-2,4-dichloro-quinazoline; 2,4-Dichloro-7,8-dimethoxy-quinazoline; 2,4-Dichloro-7,8-dimethoxyquinazoline (CAS 61948-62-7)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7,8-Dimethoxy-Quinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.