Description

8-Methoxy-2,4-Dichloroquinazoline is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive dichloro and methoxy substituents, which enable selective functionalization to create complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides that leverage the quinazoline scaffold.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for the development of organic electronic materials and advanced polymers.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	8-Methoxy-2,4-Dichloroquinazoline
CAS No.	61948-59-2
Molecular Formula	C9H6Cl2N2O
Molecular Weight	229.06 g/mol
Synonyms	2,4-Dichloro-8-methoxyquinazoline; 8-Methoxy-2,4-dichloroquinazoline; Quinazoline, 2,4-dichloro-8-methoxy-; 2,4-Dichloro-8-methoxy-quinazoline
EINECS	Contact for details

Quality Control

Our 8-Methoxy-2,4-Dichloroquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.