Description

(Trifluoromethyl)Urea is a specialized fluorinated organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group attached to a urea moiety, makes it a valuable intermediate for introducing fluorine atoms into target molecules, thereby modifying their physical, chemical, and biological properties. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for fluorinated polymers, coatings, and specialty materials with unique surface properties.
• Organic Synthesis Reagent: Employed in medicinal and combinatorial chemistry for the introduction of the -CF3 group, a critical pharmacophore.
• Biochemical Research: Utilized as a probe or modifier in studying enzyme interactions and protein binding sites.
• Fluorine Chemistry Development: A fundamental compound for methodological research in new fluorination reactions and catalysis.

Basic Information

Product Name	(Trifluoromethyl)Urea
CAS No.	61919-30-0
Molecular Formula	C₂H₃F₃N₂O
Molecular Weight	128.05 g/mol
Synonyms	Urea, N-(Trifluoromethyl)-; 1-(Trifluoromethyl)urea; N-Trifluoromethylurea; Trifluoromethylurea; (Trifluoromethyl)urea; α,α,α-Trifluoromethylurea; TFU; NSC 163049
EINECS	Contact for details

Quality Control

Our (Trifluoromethyl)Urea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material is suitable for demanding R&D and scale-up applications. Specific analytical methods, including HPLC, NMR, and IR spectroscopy, are employed to verify the product meets your technical requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.