Description

4'-Chloro-5-Methylsulfonyloxy-3-Biphenylacetic Acid, Methyl Ester is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its role as a key building block in the development of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and specialty chemical producers engaged in creating novel therapeutic agents and high-value materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic compounds.
• Organic Synthesis Building Block: Used in complex multi-step organic reactions, including cross-coupling and esterification processes, to construct advanced molecular architectures.
• Agrochemical Research: Serves as a key intermediate in the development of new crop protection agents and herbicides.
• Material Science: Employed in the research and production of specialty polymers and liquid crystals.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in medicinal and synthetic chemistry.

Basic Information

Product Name	4'-Chloro-5-Methylsulfonyloxy-3-Biphenylacetic Acid, Methyl Ester
CAS No.	61888-73-1
Molecular Formula	C₁₆H₁₅ClO₅S
Molecular Weight	354.80 g/mol
Synonyms	Methyl 2-(4'-Chloro-5-(methylsulfonyloxy)-[1,1'-biphenyl]-3-yl)acetate; 3-Biphenylacetic acid, 4'-chloro-5-[(methylsulfonyl)oxy]-, methyl ester; 4'-Chloro-5-(methylsulfonyloxy)biphenyl-3-acetic acid methyl ester; Methyl 4'-chloro-5-(methylsulfonyloxy)-[1,1'-biphenyl]-3-acetate; 61888-73-1; 4'-Chloro-5-Methylsulfonyloxy-3-Biphenylacetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 4'-Chloro-5-Methylsulfonyloxy-3-Biphenylacetic Acid, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.