Description

3Aα,3Bβ,6Aβ,6Bα-Tetrahydro-2,2,5,5-Tetramethylcyclobuta[1,2-D:3,4-D']Bis[1,3]Dioxole is a specialized, high-purity chemical intermediate characterized by its unique fused cyclobutane and dioxole structure. This compound is valued for its role as a key chiral building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and development. It is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and agrochemical sectors who require precise stereochemistry and high synthetic efficiency.

Application

This advanced intermediate is utilized in sophisticated synthetic pathways across several high-tech industries.

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for complex, stereospecific drug candidates.
• Agrochemical Synthesis: Used in the development of novel, high-performance pesticides and herbicides where specific stereochemistry impacts biological activity.
• Material Science Research: Acts as a monomer or building block for developing novel polymers and advanced organic materials with tailored properties.
• Asymmetric Catalysis: Employed as a ligand or a core structure in catalysts for enantioselective synthesis.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical spaces in organic chemistry laboratories.

Basic Information

Product Name	3Aα,3Bβ,6Aβ,6Bα-Tetrahydro-2,2,5,5-Tetramethylcyclobuta[1,2-D:3,4-D']Bis[1,3]Dioxole
CAS No.	61845-71-4
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	2,2,5,5-Tetramethyl-3a,3b,6a,6b-tetrahydrocyclobuta[1,2-d:3,4-d']bis[1,3]dioxole; Tetramethylcyclobutadioxole; (3aR,3bS,6aS,6bR)-2,2,5,5-Tetramethyltetrahydro-4H-cyclobuta[1,2-d:3,4-d']bis[1,3]dioxole; 61845-71-4; Cyclobuta[1,2-d:3,4-d']bis[1,3]dioxole, tetrahydro-2,2,5,5-tetramethyl-; Chiral cyclobutane dioxole derivative.
EINECS	Contact for details

Quality Control

Our production of 3Aα,3Bβ,6Aβ,6Bα-Tetrahydro-2,2,5,5-Tetramethylcyclobuta[1,2-D:3,4-D']Bis[1,3]Dioxole adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance in cGMP and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.