Description

n-Ethyl-n-(3-Hydroxypropyl)Nitrosamine is a specialized nitrosamine compound of significant interest in research and industrial chemistry. Its unique structure makes it a valuable intermediate and reference standard for analytical and synthetic applications. This chemical is primarily utilized by researchers and quality control laboratories in the pharmaceutical, chemical, and academic sectors for method development, impurity profiling, and toxicological studies.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and the validation of testing methods, particularly for nitrosamine detection.
• Pharmaceutical Impurity Profiling: Serves as a critical standard in the identification and quantification of nitrosamine impurities in active pharmaceutical ingredients (APIs) and drug products to ensure regulatory compliance.
• Chemical Research Intermediate: Employed in organic synthesis and chemical research for studying nitrosation reactions and developing novel compounds.
• Toxicological Studies: Used in laboratory research to investigate the metabolic pathways, genotoxicity, and carcinogenic potential of nitrosamine compounds.
• Quality Assurance & Control: Essential for establishing and verifying the accuracy of in-house testing protocols within quality control laboratories of chemical manufacturers.
• Regulatory Compliance Testing: Supports testing mandated by agencies like the FDA and EMA for monitoring nitrosamine levels in pharmaceuticals and consumer products.

Basic Information

Product Name	n-Ethyl-n-(3-Hydroxypropyl)Nitrosamine
CAS No.	61734-88-1
Molecular Formula	C5H12N2O2
Molecular Weight	132.16 g/mol
Synonyms	N-Ethyl-N-(3-hydroxypropyl)nitrosamine; N-Nitroso-N-ethyl-3-hydroxypropylamine; EHPA; 3-Hydroxypropyl ethyl nitrosamine; N-Ethyl-N-(3-hydroxypropyl)nitrous amide; N-Nitroso-N-ethyl-3-hydroxy-1-propanamine; N-Ethyl-N-(3-hydroxypropyl)-N-nitrosamine
EINECS	Contact for details

Quality Control

Our n-Ethyl-n-(3-Hydroxypropyl)Nitrosamine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) providing batch-specific results is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.