Description

(6Ar,10Ar)-3-(1,1-Dimethylheptyl)-6,6,9-Trimethyl-6A,7,10,10A-Tetrahydro-6H-Dibenzo[B,D]Pyran-1-Ol CAS NO 61597-27-1 is a synthetic cannabinoid receptor ligand with a complex dibenzopyran structure. This compound is of significant interest for advanced pharmacological research and the development of analytical reference standards. It serves as a critical intermediate and reference material for researchers in medicinal chemistry, forensic science, and neuropharmacology who are investigating cannabinoid receptor interactions and metabolic pathways.

Application

• Pharmacological Reference Standard: Used as a high-purity certified reference material (CRM) for calibrating analytical instruments in drug discovery and forensic toxicology labs.
• Medicinal Chemistry Research: Serves as a key intermediate or lead compound for synthesizing novel analogs to study structure-activity relationships (SAR) at cannabinoid receptors CB1 and CB2.
• Biochemical Assay Development: Employed in in vitro binding and functional assays to screen and characterize new therapeutic agents targeting the endocannabinoid system.
• Forensic Analysis: Provides an essential standard for the identification and quantification of synthetic cannabinoids in seized materials and biological samples using GC-MS or LC-MS/MS.
• Metabolic Studies: Used in research to identify and quantify phase I and phase II metabolites for toxicokinetic and pharmacokinetic profiling.

Basic Information

Product Name	(6Ar,10Ar)-3-(1,1-Dimethylheptyl)-6,6,9-Trimethyl-6A,7,10,10A-Tetrahydro-6H-Dibenzo[B,D]Pyran-1-Ol
CAS No.	61597-27-1
Molecular Formula	C25H38O2
Molecular Weight	370.57 g/mol
Synonyms	JWH-133; (6aR,10aR)-3-(1,1-Dimethylheptyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol; 1,1-Dimethylheptyl-δ8-THC; JWH 133; CB2 Cannabinoid Receptor Agonist JWH-133; 3-(1,1-Dimethylheptyl)-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
EINECS	Contact for details

Quality Control

Every batch of our (6Ar,10Ar)-3-(1,1-Dimethylheptyl)-6,6,9-Trimethyl-6A,7,10,10A-Tetrahydro-6H-Dibenzo[B,D]Pyran-1-Ol is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use as a research standard, including HPLC purity, identity confirmation (NMR, MS), and chiral purity verification. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.