Description

2-[(1,1-Dimethylethoxy)Methyl]Tetrahydrofuran is a versatile, highly volatile ether derivative of tetrahydrofuran, valued for its unique reactivity as a protected functional group intermediate. Its primary commercial significance lies in its role as a key building block in sophisticated organic synthesis, particularly for pharmaceuticals and fine chemicals. This compound is essential for R&D chemists and production specialists in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity, specialized intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A critical protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for introducing tetrahydrofuran-based motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its ether functionality is integral to the final product's activity.
• Fine Chemical Manufacturing: Serves as a specialized reagent for constructing complex organic molecules in research and pilot-scale production.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialty polymers with tailored properties.
• Academic & Industrial R&D: Employed in methodological development and exploratory chemistry due to its reactive tert-butoxymethyl protecting group.
• Cross-Coupling Reactions: Functions as a substrate or ligand precursor in metal-catalyzed coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	2-[(1,1-Dimethylethoxy)Methyl]Tetrahydrofuran
CAS No.	61590-76-9
Molecular Formula	C9H18O2
Molecular Weight	158.24 g/mol
Synonyms	2-(tert-Butoxymethyl)tetrahydrofuran; Tetrahydro-2-[(1,1-dimethylethoxy)methyl]furan; 2-(tert-Butoxymethyl)THF; 2-Tetrahydrofuranylmethyl tert-butyl ether; tert-Butyl 2-tetrahydrofuranylmethyl ether; 2-[(tert-Butoxy)methyl]tetrahydrofuran; THF-2-ylmethyl tert-butyl ether
EINECS	Contact for details

Quality Control

Every batch of 2-[(1,1-Dimethylethoxy)Methyl]Tetrahydrofuran is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain product integrity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.420 - 1.424
Density	0.90 - 0.94 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.