Description

3,4-Dihydro-5-(Oxiranylmethoxy)-1H-Isoquinoline-2-Carbaldehyde is a specialized heterocyclic aldehyde building block featuring an oxiranylmethoxy substituent. This compound matters as a versatile and reactive intermediate, enabling the synthesis of complex molecules through its aldehyde and epoxide functional groups. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel isoquinoline-based drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the isoquinoline scaffold can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials, where the epoxide group allows for cross-linking and polymerization.
• Chemical Biology Probes: Utilized to create fluorescent or affinity tags for studying biological processes and protein interactions.
• Academic & Contract Research: A valuable tool for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3,4-Dihydro-5-(Oxiranylmethoxy)-1H-Isoquinoline-2-Carbaldehyde
CAS No.	61563-02-8
Molecular Formula	C₁₃H₁₃NO₃
Molecular Weight	231.25 g/mol
Synonyms	5-(Oxiranylmethoxy)-3,4-dihydro-1H-isoquinoline-2-carbaldehyde; 2-Formyl-5-(glycidyloxy)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5-(2,3-epoxypropoxy)isoquinoline-2-carboxaldehyde; Glycidyl 1,2,3,4-tetrahydro-2-formyl-5-isoquinolinyl ether; 61563-02-8; 5-(2,3-Epoxypropoxy)-3,4-dihydro-1H-isoquinoline-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-5-(Oxiranylmethoxy)-1H-Isoquinoline-2-Carbaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.