Description

2-(Bromomethyl)-3-(2-Methylphenyl)Quinazolin-4(3H)-One is a specialized brominated quinazolinone derivative, a high-value intermediate prized for its reactive bromomethyl group and heterocyclic scaffold. This compound matters for its critical role in the synthesis of complex molecules, enabling the introduction of new functional groups for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinazolinone core is active.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) or other electronic materials.
• Chemical Biology & Proteomics: The reactive bromomethyl group can be utilized for labeling or cross-linking studies in probe development.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring new organic reactions and methodologies.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-complexity fine chemicals for client-specific projects.

Basic Information

Product Name	2-(Bromomethyl)-3-(2-Methylphenyl)Quinazolin-4(3H)-One
CAS No.	61554-48-1
Molecular Formula	C₁₆H₁₃BrN₂O
Molecular Weight	329.19 g/mol
Synonyms	3-(2-Methylphenyl)-2-(bromomethyl)-4(3H)-quinazolinone; 2-(Bromomethyl)-3-(o-tolyl)quinazolin-4(3H)-one; 4(3H)-Quinazolinone, 2-(bromomethyl)-3-(2-methylphenyl)-; Quinazolin-4(3H)-one, 2-(bromomethyl)-3-(2-methylphenyl)-; 61554-48-1; 2-Bromomethyl-3-(2-methylphenyl)-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-3-(2-Methylphenyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.