Description

trans-4-Methoxycyclohexanamine Hcl CAS NO 61367-41-7 is a high-purity chiral amine derivative, specifically the hydrochloride salt of the trans-isomer of 4-methoxycyclohexanamine. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and functional group compatibility. It is primarily utilized by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers for developing active ingredients and novel molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the development of advanced herbicides and plant growth regulators with specific stereochemical requirements.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways.
• Peptidomimetics and Bioactive Molecule Construction: The cyclohexylamine scaffold is incorporated into molecules designed to mimic peptide structures for biological evaluation.

Basic Information

Product Name	trans-4-Methoxycyclohexanamine Hydrochloride
CAS No.	61367-41-7
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	trans-4-Methoxycyclohexylamine Hydrochloride; (1r,4r)-4-Methoxycyclohexan-1-amine Hydrochloride; trans-4-Methoxy-1-cyclohexanamine Hydrochloride; 4-Methoxycyclohexanamine Hydrochloride (trans-); 4-Methoxycyclohexylamine Hydrochloride (trans-); (trans)-4-Methoxycyclohexanamine HCl; 4-Methoxycyclohexanamine HCl (trans isomer)
EINECS	Contact for details

Quality Control

Our trans-4-Methoxycyclohexanamine HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (trans-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.