Description

H-D-Chg-Oh Hcl is a protected amino acid derivative, specifically the hydrochloride salt of N-α-Fmoc-N-δ-Boc-L-diaminobutyric acid. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of a side-chain protected diaminobutyric acid residue. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and research reagents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid for the automated synthesis of complex peptides.
• Pharmaceutical Intermediates: Used in the research and production of peptide drugs targeting various diseases.
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Chemical Biology Research: A valuable tool for studying protein-protein interactions and enzyme mechanisms by incorporating modified amino acids.
• Antibiotic Development: Used in the synthesis of peptide antibiotics and antimicrobial peptides (AMPs).
• Material Science: Building block for peptide-based biomaterials and hydrogels.

Basic Information

Product Name	H-D-Chg-Oh Hcl
CAS No.	61367-40-6
Molecular Formula	C24H29N2O5 • HCl
Molecular Weight	476.96 g/mol
Synonyms	Fmoc-Dab(Boc)-OH • HCl; N-α-Fmoc-N-δ-Boc-L-2,4-diaminobutyric acid hydrochloride; Fmoc-L-Dab(Boc)-OH hydrochloride; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid hydrochloride; Nδ-Boc-Nα-Fmoc-L-diaminobutyric acid HCl; Boc-Dab(Fmoc)-OH • HCl; Fmoc-Dab(Boc)-OH hydrochloride salt; Protected L-Diaminobutyric Acid Derivative
EINECS	Contact for details

Quality Control

Our H-D-Chg-Oh Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.