Description

N(1), N(12)-Diethylspermine is a synthetic polyamine derivative, specifically an alkylated analog of the naturally occurring spermine. This modification enhances its stability and alters its biochemical interactions, making it a valuable tool in life science research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, molecular biology, and medicinal chemistry for studying polyamine metabolism, cell proliferation, and as a potential intermediate for novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and probe for studying polyamine transport systems, metabolism, and their role in cellular processes.
• Pharmaceutical Intermediates: Serves as a key synthetic building block in the development of novel polyamine-based drug candidates targeting various diseases.
• Cell Culture Studies: Employed to investigate the effects of modified polyamines on cell growth, differentiation, and apoptosis in vitro.
• Enzyme Inhibition Studies: Acts as a potential substrate or inhibitor for enzymes involved in polyamine biosynthesis, such as spermidine/spermine N1-acetyltransferase (SSAT).
• Molecular Biology: Utilized in studies exploring the interaction of polyamines with nucleic acids (DNA and RNA) and their impact on gene expression.

Basic Information

Product Name	N(1), N(12)-Diethylspermine
CAS No.	61345-84-4
Molecular Formula	C14H36N4
Molecular Weight	260.46 g/mol
Synonyms	N1,N12-Diethylspermine; Diethylspermine; 1,12-Diethyl-4,9-diazadodecane-1,12-diamine; N,N'-Bis(3-aminopropyl)-N,N'-diethyl-1,4-butanediamine; N1,N12-Diethyl-1,12-diamino-4,9-diazadodecane; N1,N12-Diethyl-4,9-diazadodecan-1,12-diamine
EINECS	Contact for details

Quality Control

Our N(1), N(12)-Diethylspermine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.