Description

3-Quinolinecarbonitrile, 6-Fluoro-4-Hydroxy- is a high-value fluorinated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a nitrile and a hydroxyl group on the quinoline core, makes it an essential building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated quinoline scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, liquid crystals, or organic electronic materials with specific optical or electronic properties.
• Chemical Synthesis: Versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry due to its reactive nitrile and hydroxyl functional groups.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical spaces in fluorine chemistry.

Basic Information

Product Name	3-Quinolinecarbonitrile, 6-Fluoro-4-Hydroxy-
CAS No.	61338-20-3
Molecular Formula	C10H5FN2O
Molecular Weight	188.16 g/mol
Synonyms	6-Fluoro-4-hydroxyquinoline-3-carbonitrile; 4-Hydroxy-6-fluoroquinoline-3-carbonitrile; 6-Fluoro-4-hydroxy-3-quinolinecarbonitrile; 6-Fluoro-4-hydroxy-3-cyanoquinoline; 3-Cyano-6-fluoro-4-hydroxyquinoline; 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carbonitrile; 6-Fluoro-4-hydroxy-1H-quinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

We supply 3-Quinolinecarbonitrile, 6-Fluoro-4-Hydroxy- in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.