Description

3-Quinolinecarbonitrile, 4-Hydroxy-8-(Methylsulfonyl)- is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel chemical entities. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transport or emissive layer material due to the quinoline core's electronic properties.
• Coordination Chemistry & Catalysis: Serves as a ligand for metal complexes used in catalytic processes, thanks to the hydroxy and nitrile functional groups.
• Dye & Pigment Synthesis: Employed as a building block for creating specialized quinoline-based dyes and colorants.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	3-Quinolinecarbonitrile, 4-Hydroxy-8-(Methylsulfonyl)-
CAS No.	61338-19-0
Molecular Formula	C11H8N2O3S
Molecular Weight	248.26 g/mol
Synonyms	4-Hydroxy-8-(methylsulfonyl)quinoline-3-carbonitrile; 8-Methanesulfonyl-4-hydroxyquinoline-3-carbonitrile; 4-Hydroxy-8-methanesulfonylquinoline-3-carbonitrile; 3-Cyano-4-hydroxy-8-(methylsulfonyl)quinoline; 4-Hydroxy-8-methylsulfonyl-3-quinolinecarbonitrile; Quinoline-3-carbonitrile, 4-hydroxy-8-(methylsulfonyl)-; 61338-19-0 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarbonitrile, 4-Hydroxy-8-(Methylsulfonyl)- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.