Description

3-Deoxy-D-Manno-2-Octulosonic Acid-8-Phosphoric Acid (CAS NO 61302-28-1) is a key phosphorylated sugar acid derivative, serving as a critical biochemical intermediate. Its primary commercial value lies in its role as a precursor in the biosynthesis of bacterial lipopolysaccharides (LPS) and as a valuable research tool in glycobiology and immunology. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for studying bacterial cell wall structure, vaccine development, and enzymatic pathways.

Application

• Biochemical Research: A vital substrate and intermediate for studying the biosynthesis and assembly of bacterial lipopolysaccharides (LPS) and outer membrane components.
• Enzymology Studies: Used as a specific substrate for enzymes like CMP-KDO synthetase and KDO-8-P phosphatase in metabolic pathway analysis.
• Pharmaceutical Development: Serves as a key starting material or reference standard in the research and development of novel antibiotics and anti-infective agents targeting Gram-negative bacteria.
• Vaccine Research: Employed in the investigation of bacterial pathogenesis and the development of conjugate vaccines, where understanding LPS structure is crucial.
• Glycobiology & Glycoengineering: An important building block and analytical standard for the synthesis and characterization of complex carbohydrates and glycoconjugates.
• Diagnostic Reagent Manufacturing: Used in the production of high-purity reagents and kits for microbiological and immunological assays.

Basic Information

Item	Details
Product Name	3-Deoxy-D-Manno-2-Octulosonic Acid-8-Phosphoric Acid
CAS No.	61302-28-1
Molecular Formula	C8H15O12P
Molecular Weight	310.17 g/mol
Synonyms	KDO-8-P; 3-Deoxy-D-manno-oct-2-ulosonic acid 8-phosphate; 2-Keto-3-deoxy-D-manno-octonic acid 8-phosphate; KDO 8-phosphate; 3-Deoxy-D-manno-octulosonate 8-phosphate; 8-O-Phosphono-3-deoxy-D-manno-oct-2-ulosonic acid; (4R,5R,6R)-4,5,6-Trihydroxy-2-oxo-3-(phosphonooxy)octanoic acid
EINECS	Contact for details

Quality Control

Our 3-Deoxy-D-Manno-2-Octulosonic Acid-8-Phosphoric Acid is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.