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L-Iduronic Acid Sodium Salt CAS NO 61199-83-5


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CAS No.:61199-83-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Iduronic Acid Sodium Salt is a high-purity monosaccharide derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard in the synthesis and study of glycosaminoglycans (GAGs), such as heparin and heparan sulfate. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for drug discovery, enzyme substrate studies, and the production of complex carbohydrate-based therapeutics.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of heparin analogs, anticoagulant drugs, and other glycosaminoglycan-based therapeutics.
  • Biochemical Research: Essential substrate and reference standard for studying the activity of enzymes like iduronidase and sulfotransferases involved in GAG metabolism.
  • Glycobiology Studies: Used in the structural elucidation and functional analysis of complex carbohydrates and proteoglycans.
  • Diagnostic Reagent Manufacturing: Component in the production of kits for diagnosing lysosomal storage disorders, such as Mucopolysaccharidosis I (Hurler, Scheie syndromes).
  • Cosmeceutical Development: Investigated for use in advanced skincare formulations targeting skin repair and hydration due to its role in extracellular matrix components.
  • Academic & Industrial R&D: Serves as a fundamental tool for carbohydrate chemists and molecular biologists in both university and corporate research laboratories.

Basic Information

Product Name L-Iduronic Acid Sodium Salt
CAS No. 61199-83-5
Molecular Formula C6H9NaO7
Molecular Weight 216.12 g/mol
Synonyms Sodium L-Iduronate; L-Iduronic Acid, Sodium Salt; Iduronic Acid Sodium Salt; α-L-Idopyranuronic Acid Sodium Salt; (2S,3S,4S,5R)-2,3,4,5-Tetrahydroxy-6-oxohexanoic Acid Sodium Salt; Sodium (2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate; IdA Sodium Salt
EINECS Contact for details

Quality Control

Our L-Iduronic Acid Sodium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP, ISO, and other relevant regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Specific Rotation Contact for details
Water Content (KF) ≤ 5.0%
Residue on Ignition Contact for details
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines
Microbial Enumeration Meets Ph. Eur. criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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