Description

Benzyl 3-O,4-O,6-o-Tribenzyl-α-D-Mannopyranoside Methanesulfonate is a protected glycosyl donor derivative, a key synthetic intermediate in carbohydrate chemistry. Its value lies in providing a reactive mannose building block with orthogonal protecting groups, enabling precise and efficient oligosaccharide assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing glycoconjugate vaccines, therapeutic glycoproteins, and complex bioactive oligosaccharides.

Application

• Glycoconjugate Vaccine Synthesis: A critical intermediate for constructing defined carbohydrate antigens to be conjugated to carrier proteins.
• Oligosaccharide & Glycan Assembly: Serves as a mannosyl donor in automated or solution-phase synthesis of complex N-linked and O-linked glycans.
• Pharmaceutical Intermediate: Used in the research and development of glycan-based therapeutics, including enzyme inhibitors and receptor ligands.
• Chemical Biology Probes: Building block for synthesizing labeled glycans or glycan arrays to study protein-carbohydrate interactions.
• Standards & Reference Materials: Provides a high-purity standard for analytical method development and quality control in glycan analysis.

Basic Information

Product Name	Benzyl 3-O,4-O,6-o-Tribenzyl-α-D-Mannopyranoside Methanesulfonate
CAS No.	61134-25-6
Molecular Formula	C35H38O9S
Molecular Weight	634.74 g/mol
Synonyms	Benzyl 2,3,4,6-Tetra-O-benzyl-α-D-mannopyranoside Methanesulfonate; α-D-Mannopyranoside, benzyl 2,3,4,6-tetra-O-benzyl-, methanesulfonate; Benzyl 2,3,4,6-Tetra-O-benzyl-α-D-mannoside Methanesulfonate; Tribenzyl Mannosyl Donor Methanesulfonate; Benzyl 2,3,4,6-Tetra-O-benzyl-1-O-methanesulfonyl-α-D-mannopyranoside; Mannosyl Methanesulfonate Donor
EINECS	Contact for details

Quality Control

Our Benzyl 3-O,4-O,6-o-Tribenzyl-α-D-Mannopyranoside Methanesulfonate is produced under strict quality management systems suitable for research and process development. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and lot-to-lot consistency. Certificates of Analysis (COA) with full analytical data are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged manipulation to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.