Description

n-Cyano-N'-(2-Mercaptoethyl)-N''-Methylguanidine is a specialized organic compound featuring a unique guanidine core functionalized with cyano, methyl, and mercaptoethyl groups. This molecular structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for applications in drug discovery and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Bioconjugation Reagent: Utilized in the development of antibody-drug conjugates (ADCs) or protein labeling due to its reactive thiol (-SH) and cyano groups.
• Chemical Research & Development: Serves as a versatile scaffold for creating libraries of guanidine-based compounds for biological screening.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides or herbicides where the guanidine moiety imparts biological activity.
• Polymer Modification: Can be used to introduce functional groups into polymer chains to alter material properties like adhesion or biocompatibility.
• Catalyst Ligand Precursor: Potential use in preparing ligands for metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	n-Cyano-N'-(2-Mercaptoethyl)-N''-Methylguanidine
CAS No.	61085-25-4
Molecular Formula	C6H11N5S
Molecular Weight	185.25 g/mol
Synonyms	1-Cyano-3-(2-mercaptoethyl)-2-methylguanidine; 2-Methyl-1-cyano-3-(2-mercaptoethyl)guanidine; N-Cyano-N'-(2-mercaptoethyl)-N''-methylguanidine; Guanidine, N-cyano-N'-(2-mercaptoethyl)-N''-methyl-; (2-Mercaptoethyl)(methyl)cyanoguanidine; CAS 61085-25-4
EINECS	Contact for details

Quality Control

Our n-Cyano-N'-(2-Mercaptoethyl)-N''-Methylguanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.