Description

cis-4-(1,1-Dimethylethyl)-α-Methylcyclohexylmethanol is a high-purity, specialty tertiary alcohol characterized by its unique sterically hindered cyclohexyl structure. This compound is valued as a versatile chiral intermediate and building block in advanced organic synthesis, particularly for the development of complex molecules. It is essential for research and production in the pharmaceutical, agrochemical, and fragrance industries, where its specific stereochemistry and functional groups enable the creation of high-value, performance-driven end products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of sterically hindered drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structure contributes to biological activity and selectivity.
• Fragrance and Flavor Ingredient: Serves as a precursor for musky or woody aroma chemicals due to its bulky, lipophilic character.
• Ligand and Catalyst Development: Employed in the research and manufacture of specialized ligands for asymmetric catalysis and metal complexes.
• Polymer Modification: Acts as a monomer or chain-transfer agent to introduce steric hindrance and modify the properties of specialty polymers.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D in exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	cis-4-(1,1-Dimethylethyl)-α-Methylcyclohexylmethanol
CAS No.	61065-77-8
Molecular Formula	C₁₂H₂₄O
Molecular Weight	184.32 g/mol
Synonyms	cis-4-tert-Butyl-α-methylcyclohexanemethanol; (1R,4S)-4-tert-Butyl-1-methylcyclohexanemethanol; 4-tert-Butyl-1-methyl-cyclohexanemethanol (cis-); L-Menthol, 8-tert-butyl-; Ambroxide precursor intermediate; Cyclohexanemethanol, 4-(1,1-dimethylethyl)-α-methyl-, cis-; Tertiary alcohol C12
EINECS	Contact for details

Quality Control

Our cis-4-(1,1-Dimethylethyl)-α-Methylcyclohexylmethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Chiral Purity (enantiomeric excess)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.