Description

(R)-(-)-3-Chloromandelic Acid CAS NO 61008-98-8 is a high-purity chiral building block and resolving agent of significant importance in asymmetric synthesis. Its value lies in its utility for the preparation of enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries that require precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
• Chiral Resolving Agent: Used for the optical resolution of racemic mixtures of amines, amino acids, and other basic compounds due to its acidic enantiopure structure.
• Asymmetric Synthesis Catalyst Ligand: Serves as a precursor for ligands in metal-catalyzed asymmetric reactions, such as hydrogenations and oxidations.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process chemistry research.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where chirality impacts product performance.

Basic Information

Product Name	(R)-(-)-3-Chloromandelic Acid
CAS No.	61008-98-8
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	(R)-3-Chloromandelic Acid; (R)-(-)-3-Chloro-α-hydroxybenzeneacetic Acid; (R)-2-Hydroxy-2-(3-chlorophenyl)acetic Acid; (R)-3-Chloro-α-hydroxybenzenacetic Acid; (R)-3-Chlorophenylglycolic Acid; (R)-α-Hydroxy-3-chlorophenylacetic Acid; (R)-O-(3-Chlorophenyl)glycolic Acid; (R)-CMA
EINECS	Contact for details

Quality Control

Our (R)-(-)-3-Chloromandelic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.