Description

Ethanone, 2-Chloro-1-(3-Chloro-2-Methylphenyl)- (9Ci) is a specialized chlorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists and process engineers working on novel active ingredients, where high-purity intermediates are critical for successful scale-up and regulatory approval.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with complex halogenated aromatic backbones.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its chlorinated structure contributes to biological activity.
• Organic Synthesis Building Block: Serves as a versatile electrophile or coupling partner in cross-coupling reactions, Friedel-Crafts acylations, and other transformations to introduce functionalized acetophenone motifs.
• Material Science Research: Investigated as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and photographic chemicals requiring specific halogen-substituted aromatic ketones.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(3-Chloro-2-Methylphenyl)- (9Ci)
CAS No.	60988-74-1
Molecular Formula	C9H8Cl2O
Molecular Weight	203.07 g/mol
Synonyms	2-Chloro-1-(3-chloro-2-methylphenyl)ethanone; 1-(3-Chloro-2-methylphenyl)-2-chloroethanone; 2-Chloro-3'-chloro-2'-methylacetophenone; α,3-Dichloro-2-methylacetophenone; NSC 403119; 2-Chloro-1-(3-chloro-o-tolyl)ethanone; Ethanone, 2-chloro-1-(3-chloro-2-methylphenyl)-
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for this advanced intermediate. Production adheres to cGMP guidelines where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our standard analytical suite includes HPLC, GC, NMR, and IR spectroscopy to verify specifications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.