Description

5-(1-Adamantyl)-2H-Tetrazole is a high-value, functionalized heterocyclic compound featuring the unique adamantane cage structure. This molecular architecture imparts significant thermal stability and lipophilicity, making it a crucial intermediate for advanced material and pharmaceutical synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the blood-brain barrier permeability conferred by the adamantyl group.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides where the tetrazole moiety acts as a bioisostere for carboxylic acids, improving metabolic stability.
• Material Science: Employed as a monomer or cross-linking agent in the production of high-performance polymers, resins, and metal-organic frameworks (MOFs) with enhanced thermal properties.
• Ligand in Catalysis: Functions as a stabilizing ligand for transition metal catalysts in various organic transformation reactions, including click chemistry (CuAAC).
• Energetic Materials Research: Investigated for potential use in the formulation of high-energy-density materials (HEDMs) due to the high nitrogen content of the tetrazole ring.

Basic Information

Product Name	5-(1-Adamantyl)-2H-Tetrazole
CAS No.	60798-89-2
Molecular Formula	C11H16N4
Molecular Weight	204.27 g/mol
Synonyms	1-Adamantyltetrazole; 5-(1-Adamantyl)-1H-Tetrazole; 5-(Tricyclo[3.3.1.1³,⁷]dec-1-yl)-1H-tetrazole; 5-(Adamantan-1-yl)-1H-tetrazole; Adamant-1-yl-1H-tetrazole; NSC 405124; 5-(1-Adamantyl)tetrazole
EINECS	Contact for details

Quality Control

Every batch of 5-(1-Adamantyl)-2H-Tetrazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of research and development, as well as scale-up processes. A detailed Certificate of Analysis (COA) including results for purity, identity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.