Description

5-tert-Butyl-2-Chlorobenzoic Acid is a high-purity, versatile benzoic acid derivative characterized by its specific substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate and a valuable building block in organic synthesis, enabling the creation of complex molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a sterically hindered benzoic acid moiety.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Polymer Additive: Can be employed to modify polymer properties or as a monomer in the production of specialty polyesters and polyamides.
• Organic Synthesis Reagent: A versatile starting material for introducing the 5-tert-butyl-2-chlorophenyl group into more complex molecular architectures via reactions like esterification, amidation, or metal-halogen exchange.
• Material Science Research: Investigated for use in the development of liquid crystals, organic semiconductors, and other advanced functional materials.

Basic Information

Item	Details
Product Name	5-tert-Butyl-2-Chlorobenzoic Acid
CAS No.	60772-72-7
Molecular Formula	C11H13ClO2
Molecular Weight	212.67 g/mol
Synonyms	2-Chloro-5-tert-butylbenzoic acid; 5-(1,1-Dimethylethyl)-2-chlorobenzoic acid; Benzoic acid, 2-chloro-5-(1,1-dimethylethyl)-; 2-Chloro-5-tert-butylbenzoic acid; 5-tert-Butyl-2-chlorobenzoic acid; 2-Chloro-5-(tert-butyl)benzoic acid; 5-(tert-Butyl)-2-chlorobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-2-Chlorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the exacting standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.