Description

5-tert-Butyl-2-Nitrobenzoic Acid is a high-purity, synthetically valuable aromatic carboxylic acid derivative, distinguished by its tert-butyl and nitro substituents. This compound serves as a critical building block and intermediate in advanced organic synthesis, enabling the creation of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring a sterically hindered benzoic acid scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where its specific substitution pattern imparts desired biological activity.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., amide formation, esterification) and as a starting material for further functionalization of the aromatic ring in fine chemical production.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic systems for asymmetric synthesis and polymerization processes.
• Material Science Research: Investigated for the development of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Dye and Pigment Intermediate: Functions as an intermediate in the synthesis of complex azo dyes and organic pigments, contributing to color fastness and stability.

Basic Information

Product Name	5-tert-Butyl-2-Nitrobenzoic Acid
CAS No.	60772-71-6
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	2-Nitro-5-tert-butylbenzoic Acid; 5-(1,1-Dimethylethyl)-2-nitrobenzoic Acid; Benzoic acid, 5-(1,1-dimethylethyl)-2-nitro-; 5-tert-Butyl-2-nitrobenzoic acid; 2-Nitro-5-(tert-butyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-2-Nitrobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.