Description

7-(Benzyloxy)-2,4-Dichloro-6-Methoxyquinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for drug discovery and production.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted anticancer agents and other therapeutic molecules.
• Kinase Inhibitor Development: Serves as a core scaffold for creating novel compounds that modulate kinase activity, a major focus in oncology research.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Employed in the optimization and commercial-scale manufacturing of complex drug candidates.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API production.

Basic Information

Product Name	7-(Benzyloxy)-2,4-Dichloro-6-Methoxyquinazoline
CAS No.	60771-18-8
Molecular Formula	C₁₆H₁₂Cl₂N₂O₂
Molecular Weight	335.18 g/mol
Synonyms	2,4-Dichloro-6-methoxy-7-(phenylmethoxy)quinazoline; 6-Methoxy-7-benzyloxy-2,4-dichloroquinazoline; 7-Benzyloxy-2,4-dichloro-6-methoxyquinazoline; 2,4-Dichloro-7-(benzyloxy)-6-methoxyquinazoline; Quinazoline, 2,4-dichloro-6-methoxy-7-(phenylmethoxy)-; 60771-18-8; BDBM50150057
EINECS	Contact for details

Quality Control

Our 7-(Benzyloxy)-2,4-Dichloro-6-Methoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.