Description

4-tert-Butylcalix[4]arene CAS NO 60705-62-6 is a versatile macrocyclic compound belonging to the calixarene family, characterized by a cup-shaped molecular structure formed from phenolic units. This unique architecture makes it an excellent host molecule for selectively binding various guest ions and neutral molecules through supramolecular interactions. It is a critical building block and research chemical for scientists and engineers in advanced material science, pharmaceutical development, and environmental chemistry, where molecular recognition and selective complexation are paramount.

Application

• Supramolecular Chemistry Research: Fundamental studies in host-guest chemistry, molecular recognition, and the construction of complex molecular assemblies and sensors.
• Ion-Selective Electrodes & Sensors: Development of chemical sensors and electrode membranes for the selective detection and quantification of specific metal ions (e.g., alkali, alkaline earth, or heavy metals).
• Catalysis & Separation Science: Use as a ligand or stationary phase modifier for chiral separations in chromatography or as a catalyst support in specialized organic synthesis.
• Nanomaterial & Polymer Modification: Functional component for creating advanced polymers, dendrimers, or surface coatings with tailored properties like selective permeability or adhesion.
• Pharmaceutical & Drug Delivery: Investigation as a potential drug carrier or encapsulating agent for controlled release formulations due to its cavity structure.
• Wastewater Treatment: Research into extraction and removal processes for specific pollutants or metal ions from industrial effluents.

Basic Information

Product Name	4-tert-Butylcalix[4]arene
CAS No.	60705-62-6
Molecular Formula	C44H56O4
Molecular Weight	648.92 g/mol
Synonyms	p-tert-Butylcalix[4]arene; 5,11,17,23-Tetra-tert-butyl-25,26,27,28-tetrahydroxycalix[4]arene; Calix[4]arene, 5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrahydroxy-; Tetra-p-tert-butylcalix[4]arene; 25,26,27,28-Tetrahydroxy-5,11,17,23-tetra-tert-butylcalix[4]arene; 5,17-Di-tert-butyl-26,28-dihydroxy-11,23-di-tert-butylcalix[4]arene (common misnomer); Host molecule; Macrocyclic phenol
EINECS	Contact for details

Quality Control

Our 4-tert-Butylcalix[4]arene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and melting point determination. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	342 - 346 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.