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6'-Methoxycinchonan-9(S)-Ol Mono[(1S)-7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptane-1-Methanesulphonate] CAS NO 60662-74-0


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CAS No.:60662-74-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6'-Methoxycinchonan-9(S)-Ol Mono[(1S)-7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptane-1-Methanesulphonate] is a high-purity, chiral organocatalyst and synthetic intermediate derived from cinchona alkaloid chemistry. This compound matters for its critical role in facilitating asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals with high stereoselectivity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients and specialty compounds.

Application

  • Asymmetric Organocatalysis: A key chiral catalyst for enantioselective reactions such as Michael additions, aldol reactions, and phase-transfer catalysis.
  • Pharmaceutical Intermediate: Used in the synthesis of complex, chiral drug molecules, particularly in the development of antiviral and central nervous system (CNS) agents.
  • Agrochemical Synthesis: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Fine Chemical Production: Serves as a building block for high-value specialty chemicals, flavors, and fragrances requiring specific chirality.
  • Academic & Process R&D: A valuable reagent for method development and scaling up new asymmetric synthetic routes in laboratory and pilot plant settings.
  • Ligand for Metal Complexes: Can be utilized to modify metal catalysts, enhancing their selectivity and activity in various transformation processes.

Basic Information

Item Detail
Product Name 6'-Methoxycinchonan-9(S)-Ol Mono[(1S)-7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptane-1-Methanesulphonate]
CAS No. 60662-74-0
Molecular Formula C30H42N2O6S
Molecular Weight 558.73 g/mol
Synonyms 9(S)-Hydroxy-6'-methoxycinchonan Mono[(1S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate]; (8α,9R)-6'-Methoxycinchonan-9-ol 1-Camphorsulfonate; Cinchona Alkaloid Derivative; 6'-Methoxycinchonan-9-ol Camphorsulfonate Salt; Asymmetric Phase-Transfer Catalyst; PTC Catalyst; O-Methylquinine Camphorsulfonate; Contact for additional synonyms.
EINECS Contact for details

Quality Control

Our production of this chiral compound adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral chromatography, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Enantiomeric Excess (ee) ≥ 99.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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