Description

6-Chloro-2-(Chloromethyl)-4-(2-Fluorophenyl)-1,2-Dihydroquinazoline 3-Oxide is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry where its unique quinazoline oxide scaffold is leveraged for biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex nitrogen-containing heterocycles in organic and medicinal chemistry.
• Academic & R&D Laboratories: Employed in fundamental research to study chemical reactivity, reaction mechanisms, and to create libraries of compounds for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials, such as ligands for catalysts or photoactive compounds.

Basic Information

Product Name	6-Chloro-2-(Chloromethyl)-4-(2-Fluorophenyl)-1,2-Dihydroquinazoline 3-Oxide
CAS No.	60656-72-6
Molecular Formula	C15H11Cl2FN2O
Molecular Weight	337.16 g/mol
Synonyms	6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-oxide; 2-(Chloromethyl)-6-chloro-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-oxide; 4-(2-Fluorophenyl)-6-chloro-2-(chloromethyl)-1,2-dihydroquinazoline 3-oxide; Quinazoline, 6-chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydro-, 3-oxide; CAS 60656-72-6
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(Chloromethyl)-4-(2-Fluorophenyl)-1,2-Dihydroquinazoline 3-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.